Why is oxycontin so dangerous




















Due to the fact that it can contain a large amount of oxycodone, it has become one of the most abused prescription drugs in the United States. OxyContin is a semi-synthetic opioid analgesic prescribed for chronic or long-lasting pain. OxyContin can contain between 10 and 80 milligrams of oxycodone in a timed-release tablet, compared to about five milligrams a day in Percodan.

Generally, OxyContin is prescribed to be taken twice a day, a benefit over other pain-relieving medications that have to be taken several times a day. OxyContin is available in tablet form in seven dosage levels from 10 to 80 milligrams.

It is usually prescribed to help patients with chronic pain, such as back and neck pain. It may also be prescribed to cancer patients to help decrease pain and improve function. People who misuse OxyContin use the medicine in amounts or ways that are not prescribed or intended. They can either crush the tablet and ingest or snort it, or they dilute it in water and inject it.

Crushing or diluting the tablet disarms the timed-release action of the medication, but crushing OxyContin in this way can give the user a potentially fatal dose. The drugmaker, Purdue Pharma LP, made changes so that breaking up the tablet does not immediately release oxycodone. Also, if someone attempts to dissolve these new tablets for syringe injection, the liquid becomes gummy.

Despite these measures, the FDA continues to admit that abuse and misuse of OxyContin remain possible. Further, there is an increase in OxyContin abusers who are turning to heroin because it is a significantly lower-cost opioid.

Some of the street names for OxyContin include Oxy, O. It is frequently mispronounced and misspelled as "oxycotton. For more mental health resources, see our National Helpline Database. Under the prescribed dosage, OxyContin is an effective pain reliever. When crushed and snorted or injected, the drug produces a quick and powerful "high" that some abusers compare to the feeling they get when doing heroin.

OxyContin, like heroin and other opioids, is a central nervous system depressant. An overdose can cause respiratory failure and death. Some symptoms of OxyContin overdose include:. If you believe someone has taken an overdose of OxyContin, call immediately.

Narcan naloxone hydrochloride is an emergency medication designed to counteract an opioid overdose. First-responders can use it to revive someone if they can reach them soon enough. Contact a treatment provider today for help with this dangerous addiction. After graduation, he decided to pursue his passion of writing and editing. All of the information on this page has been reviewed and verified by a certified addiction professional. Theresa is also a Certified Professional Life Coach and volunteers at a local mental health facility helping individuals who struggle with homelessness and addiction.

Theresa is a well-rounded clinician with experience working as a Primary Addiction Counselor, Case Manager and Director of Utilization Review in various treatment centers for addiction and mental health in Florida, Minnesota, and Colorado.

She also has experience with admissions, marketing, and outreach. As a proud recovering addict herself, Theresa understands first-hand the struggles of addiction. There is no limit to what Theresa is willing to do to make a difference in the field of Addiction!

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What we do see empirically is that there are differences in side effect profile: morphine's histaminergic proclivity does tend to yield more pruritis for example, but oxycodone's KOR proclivity yields markedly worse withdrawal and hyperalgesia. And its disproportionately effective CNS mu-receptor activity yields unparalleled hedonic reward and conditioning.

Along those lines, many respondents to the initial article vocalized umbrage at the allegation that oxycodone results in a "high. There's another clinical question worth answering here, brought up by at least one respondent: what about pharmacogenomics?

Basically the argument goes something like this: some people by virtue of P variability either CYP2D6, responsible for generating oxymorphone, or CYP3A4, responsible for the essentially non-active noroxycodone are more prone to become addicted to oxycodone. The issue has been looked into in some depth, with numerous studies examining whether poor or ultrarapid metabolizer status at either locus are more or less likely to misuse and abuse oxycodone.

Data from the DAWN network show that oxycodone is associated with more ED visits than any other individual drug any guesses as to number two? That's right — alprazolam. Is the drug that much more dangerous? If so, that alone would argue for serious re-thinking of its place in any formulary or practice.



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